22 year old female with complaints of nausea , decreased appetite and pain in the epigastric region since 4 days


































DR. YAMINI ( INTERN) 
DR. AMULYA ( INTERN) 
DR. SURYA PRADEEP ( INTERN) 
DR. ASHA KIRAN ( INTERN) 
DR. JAYANTH ( INTERN) 
DR. VAMSHI ( INTERN) 
DR. PRADEEP ( PG 1st YEAR)
DR. CHANDANA ( PG 1st YEAR) 
DR. USHA ( PG 2nd YEAR) 
DR. SUFIYA ( PG 3rd YEAR) 
DR. SATISH ( PG 3rd YEAR) 
Faculty : DR. VIJAYALAXMI ( Asst. Prof.)
DR. RAKESH BISWAS HOD




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Here is a case i have seen:
Admission under unit 2 on 26/01/2021(Day-0)
A 22 year old female who is a housewife resident of vemulapally  mandal came to casualty with a chief complaint of nausea since 4 days , decreased appetite since 4 days and pain in the epigastric region since 4 days. 
HOPI: patient was apparently asymptomatic 4 days back later she had c/o nausea since 4 days , decreased appetite since 4 days, intake of food followed by vomitings , pain abdomen at epigastric region since 4 days. 
C/o bilateral swelling of lower limbs up to ankle since 4 days which is pitting type , c/o constipation since 4 days . No h/o Fever , cough, cold, burning micturition .
normal urine output .
H/o similar complaints 15 days back (admitted in outside hospital for 2 days). 
Pt is a k/c/o type 1 DM diagnosed at the age of 12 years when admitted in hospital ( kamineni hospitals) for fever and is on insulin therapy ( mixtard). 
Not a k/c/o HTN, Asthma , TB, CAD and no h/o blood transfusions 
Personal history: she is a vegetarian and with h/o decreased appetite 
No known allergies 
No addictions.
Menstrual history : she attained menarche at the age of 12 years with regular cycles of 3/28, no dysmenorrhea LMP: 2 days back
General examination: 
Patient is conscious , coherent , cooperative oriented to time, place, person 
Pallor is present , no signs of icterus, cyanosis, clubbing 
B/L pedal edema pitting  type present up to ankles 
Signs of malnutrition and dehydration present 
Vitals: temp: 97OF 
PR : 120bpm regular rhythm normal volume 
RR : 16cpm 
BP: 200/120 mm of hg 
SpO2 : 98% on RA 
GRBS: 534 mg/dl 





Systemic examination: 
CVS: S1 S2 heard , no murmurs 
RS : NVBS heard , no added sounds 
CNS: no focal deficits 
P/A : soft , tenderness present in epigastric region , bowel sounds heard. 
           PROVISIONAL DIAGNOSIS: 
Diabetic ketoacidosis with ? Hypertensive urgency  with k/c/o DM type 1 with anaemia( microcytic hypochromic) under evaluation. 
 INVESTIGATIONS: 











 










Treatment 
  1. NBM till further orders 
  2. Inj. HAI 40 units in 49ml of NS/ IV @6ml/ hour 
  3. Inj. PANTOP 40mg / IV/ OD 
  4. Inj. ZOFER 4mg/ IV / TID 
  5. TAB. NICARDIA 10mg/ PO/ Stat 
  6. IVF NS @ 50ml/ hour 
  7. Tab. TELMA 20mg/ PO/ OD
  8. Strict I/O charting 
  9. BP charting 2nd hourly 
  10. GRBS charting 1 hourly 
  11. Temp/ PR/ BP/ spo2 charting 4th hourly 

DAY-2 (28-1-2021)

Patient complaining of swelling around eyes and watering from the eyes since yesterday afternoon. No fever spikes overnight. 
Patient is feeling hungry. Patient didn’t pass stools but passing flatus. 
Examination: 
Patient is conscious, coherent, cooperative 
B/L pedal edema pitting type present upto midcalf 
Raised JVP 
Vitals: 
Temp : afebrile to touch 
BP: 150/100 mm of hg 
PR: 94bpm normal volume, regular rhythm 
SpO2: 98% on RA 
RS: BAE + 
CVS: S1S2 heard 
CNS: no focal deficits 
P/A : soft non tender BS+ 

INVESTIGATIONS: 








PROVISIONAL DIAGNOSIS: 
DIABETIC KETOACIDOSIS ( RESOLVED) 
WITH HYPERTENSIVE URGENCY( DENOVO) 
WITH CHOLELITHIASIS WITH HYPOPROLIFERATIVE ANEMIA (?IRON DEFICIENCY) SECONDARY TO NUTRITIONAL WITH K/C/O TYPE 1 DM WITH HTN AND DIABETIC RETINOPATHY CHANGES ? DIABETIC NEPHROPATHY. 

TREATMENT: 
Rx: 
  1.  Salt restricted diet ( <2.4g/day)
  2. Strict diabetic diet 
  3. Day 2 TAB. CEFIXIME 200 mg/PO/ BD
  4. TAB. ONDEN 4mg  /PO/ SOS 
  5. TAB. TELMA-H 40mg/ PO/ OD 
  6. TAB. ALDACTONE 50mg/ PO/ BD 
  7. Inj. HAI /SC/TID 
  8. Syp. CITRALKA 10ml in 1 glass of water /PO/ TID 
  9. TAB. PCM 650mg / PO/ SOS
  10. Syp. CREMAFFIN 15ml / PO/ BD
  11. GRBS charting 6th hourly 
  12. BP/ PR/ SpO2/ Temp charting 4th hourly 
  13. Strict I/O charting

DAY-3 (29-1-2021)

S - complaints of peri orbital puffiness left eye(Due to depended part sleeping over night)

O -  patient is c/c/c
     BP - 160/100mm hg
     PR - 122 BPM
     Spo2- 98% on RA
     CVS -  S1 S2 heard, no murmurs
     RS - BAE present
     CNS - no focal deficit

A - DKA (resolved), denovo hypertension,Type-1DM with mild daibetic & Hypertensive changes

P - 
1. Salt restricted diet 
2. Strict diabetic diet 
3. TAB. CEFIXIME 200mg/PO/BD
4. TAB. ONDEN 4mg/PO/ SOS
5. TAB. TELMA- H (40/12.5mg) /PO/BD
6. Inj. HAI/SC/ TID 
7. Syp.CITRALKA 10ml in 1 glass of water / PO/ TID 
8. Syp. CREMAFFIN 15ml/PO/TID
9, GRBS charting 6th hourly 
10. BP/PR/ SPO2 /Temp charting 4th hourly 
11. TAB. ATORVASTATIN 10mg/ PO/ HS 
12. Eye drops LUBREX / QID
13. Inj. LASIX / IV/ TID 


INVESTIGATIONS: 



DAY- 4 (30-1-2021)
S -  4 episodes of vomitings yesterday night, where the first episodes content was food she had eaten and then it was only water . Complaining of retrosternal burning sensation.

O -  patient is conscious , coherent and cooperative. Peri orbital puffiness subsided significantly.
     BP - 160/110mm hg
     PR - 136 BPM
     Spo2- 98% on RA
     CVS -  S1 S2 heard, no murmurs
     RS - BAE present
     CNS - no focal deficit

A - DKA (resolved), denovo hypertension,?Glomerulo nephritis

P - 
1. Salt restricted diet 
2. Strict diabetic diet 
3. Inj. LASIX /IV/ BD 
4. Inj. ONDEN 4mg/IV/ TID 
5. Tab. TELMA-H (40/12.5mg) /PO/ BD 
6. Inj. INSULIN S/C     
               BBF.  BL.  BD
Reg.        5.      5.     5 
NPH.       8.      -       7 
7. Tab. ATORVASTATIN 10mg/ PO/HS 
8. Syp. CREMAFFIN 15ml/ PO/ BD
9. LUBREX eye drops / QID 
10. GRBS charting 6th hourly 
11. Strict i/o charting 
12. BP/PR/ RR/ SpO2 / temp charting 6th hourly 
13. Tab. CEFIXIME 200mg / PO/ BD 
14. Inj. PAN 80mg in 50ml NS over 2 hours 
INVESTIGATIONS: 
  
DAY-5 (31-01-2021)
S -  2-3 episodes of vomitings yesterday night, where content was food she had eaten and Complaining of retrosternal burning sensation , neck pain present 

O -  patient is conscious , coherent and cooperative. Peri orbital puffiness subsided significantly. 
     BP - 140/100 mm hg
     PR - 117BPM
     Spo2- 98% on RA
     CVS -  S1 S2 heard, no murmurs
     RS - BAE present
     CNS - no focal deficit

A - DKA (resolved), denovo hypertension,?Glomerulo nephritis

P - conservative treatment

INVESTIGATIONS: 


DAY- 6 (1-02-2021)
S-5Episodes of vomitings yesturday evening,Neck pain(Relieved Today)

O-Pt is c/c/c 
Bp-140/100 mmhg
PR-130/min
Spo2-98% on room air
Cvs-S1 S2 heard,No murmurss
RS-BAE +
CNS-No focal deficit

A-DKA(Resolved),Hypertensive Urgency(Resolved),Denovo HTN,Diabetic Nephropathy(Stage-3)
     
P-Conservative
INVESTIGATIONS: 


 

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